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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYOC
All Species:
17.88
Human Site:
T290
Identified Species:
43.7
UniProt:
Q99972
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99972
NP_000252.1
504
56972
T290
E
T
T
W
R
I
D
T
V
G
T
D
V
R
Q
Chimpanzee
Pan troglodytes
XP_513995
490
55353
T276
E
T
T
W
R
I
D
T
V
G
T
D
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001099905
491
55540
T277
E
T
T
W
R
I
D
T
V
G
T
D
V
R
Q
Dog
Lupus familis
XP_537805
678
75531
D459
D
N
R
V
W
Y
M
D
G
Y
H
N
N
R
F
Cat
Felis silvestris
Mouse
Mus musculus
O70624
490
55295
T276
E
S
T
W
R
I
D
T
V
G
T
E
I
R
Q
Rat
Rattus norvegicus
Q9R1J4
502
56424
T288
E
T
T
W
R
I
D
T
V
G
T
G
I
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515085
485
53353
G273
T
W
R
V
D
A
I
G
T
N
V
R
Q
V
A
Chicken
Gallus gallus
Q9IAK4
485
55511
V274
S
Y
H
N
N
R
F
V
R
E
Y
K
S
M
A
Frog
Xenopus laevis
B5MFE9
392
45091
P181
N
D
T
V
Y
M
Y
P
R
M
K
E
F
T
L
Zebra Danio
Brachydanio rerio
Q29RB4
390
44487
F179
D
D
N
T
V
F
E
F
G
T
V
R
E
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
94.2
25.8
N.A.
79.5
80.9
N.A.
58.5
29.1
25
23.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.6
96.2
42
N.A.
87.5
89
N.A.
73.2
49.2
42.6
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
80
86.6
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
93.3
N.A.
0
0
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
20
0
0
10
0
50
10
0
0
0
30
0
0
0
% D
% Glu:
50
0
0
0
0
0
10
0
0
10
0
20
10
0
0
% E
% Phe:
0
0
0
0
0
10
10
10
0
0
0
0
10
10
10
% F
% Gly:
0
0
0
0
0
0
0
10
20
50
0
10
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
10
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
10
0
0
10
0
0
0
10
0
% M
% Asn:
10
10
10
10
10
0
0
0
0
10
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
50
% Q
% Arg:
0
0
20
0
50
10
0
0
20
0
0
20
0
60
0
% R
% Ser:
10
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
10
40
60
10
0
0
0
50
10
10
50
0
0
10
10
% T
% Val:
0
0
0
30
10
0
0
10
50
0
20
0
30
10
0
% V
% Trp:
0
10
0
50
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
10
10
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _